I can't use just one setting for everything. Not all silver bullets that work for everybody.
Maybe some though.
It depends on the application I'm filming for. If I need a quick result, immediately viewable, or I want to use the 2x zoom (which is actually cropping without pixel loss), I shoot in 1080p, color normal, auto WB, sharpness -1, everything else neutral or zero, camera on manual.
If I need to edit later, I shoot in 4K, D-Log with -1 sharpness, color flat, saturation -1 (again camera on manual). Then I post process in DaVinci Resolve, using my own (or bought) custom LUT library, and edit in Premiere Pro.
Google Inspire1 LUT and you get a wealth of information.
It's advisable to use a shutter speed not higher than twice the frame rate setting. It is common to use the highest frame rate, which allows for the fastest shutter speed. Unless you want a cinematic effect, then you want lower frame rates. Bring the shutter speed down with appropriate HD filters. Using a good sun hood helps if you are forced into higher shutter speeds. Or if you need to shoot fast action. A little less sharpness helps in the busy shots (trees, leaves, brick walls, diagonals etc). Most of the times -1 in sharpness is a good thing. You can always boost that back in post processing.
But I'm sure others might use other settings that work better for them.